Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity linked to bortezomib, a proteasome inhibitor used in the remedy of a number of myeloma. Its synthesis or research is essential for making sure the purity and basic safety with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug Utilized in the therapy of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-ten-one): A crucial compound within the synthesis of imatinib, a drug that targets unique different types of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers like breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their research is essential for optimizing the generation procedure and guaranteeing high purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is made use of to take care of breast cancer, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the procedure of breast most cancers. Different intermediates help in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers like ovarian, breast, and lung cancer.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the treatment of colorectal cancer and modest mobile CAS NO. 302964-24-5 lung most cancers.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved with the synthesis of adamantane derivatives, that have many applications, which includes antiviral Houses.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for style two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, which happen to be Employed in food stuff, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A precursor from the synthesis of canagliflozin, a medication applied 2-deoxy-2 to control form two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).